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Bcl-2 Polyclonal Antibody #40639

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameBcl-2 Polyclonal Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ApplicationsWB IHC IF ELISA
  • Species ReactivityHu Ms Rt
  • SpecificityBcl-2 Polyclonal Antibody detects endogenous levels of Bcl-2 protein.
  • Immunogen Typepeptide
  • Immunogen DescriptionSynthesized peptide derived from human Bcl-2 around the non-phosphorylation site of T69.
  • Target NameBcl-2
  • Alternative Names    BCL2; Apoptosis regulator Bcl-2
  • Accession No. Swiss-Prot: P10415
    NCBI Gene ID: 596
  • UniprotP10415
  • Gene ID596;
  • SDS-PAGE MW 26kd
  • Concentration 1mg/ml
  • Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Storage Store at -20˚C/1 year
Application Details

Published Papers

Exosomal HSP90 induced by remote ischemic preconditioning alleviates myocardial ischemia/reperfusion injury by inhibiting complement activation and inflammationInBMC Cardiovasc DisordOn2023 Feb 1byXiao-Fang Cheng 1, Shi-Tao He et al..PMID: 36726083, , (2023),
PMID: 36726083
Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo. In Int J Biol Sci on 2022 Jul 11 by Tangming Peng, Shuai Li ,et al..PMID:35864966, , (2022),
PMID: 35864966
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro. In Environ Toxicol on 2022 Jan by Caixia Wang, Zhangyu Gu,et al..PMID:34612572, , (2022),
PMID: 34612572
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway. In Cell Death Dis on 2021 Jun 3 by Chang Jia, Yingzhi Zhuge, et al..PMID:34083516, , (2021),
PMID: 34083516
View All Published Papers Artemether confers neuroprotection on cerebral ischemic injury through stimulation of the Erk1/2-P90rsk-CREB signaling pathway. In Redox Biol on 2021 Oct by Shuai Li, Tangming Peng,et al..PMID:34303216, , (2021),
PMID: 34303216
Opposing functions of β-arrestin 1 and 2 in Parkinson's disease via microglia inflammation and Nprl3. In Cell Death Differ on 2021 Jun by Yinquan Fang, Qingling Jiang, et al..PMID:33686256, , (2021),
PMID: 33686256
Exploring the Therapeutic Mechanism of Tingli Dazao Xiefei Decoction on Heart Failure Based on Network Pharmacology and Experimental Study. In Evid Based Complement Alternat Med on 2021 Nov 25 by Dan-Dan Zhao, Xiao-Qing Zhang,et al..PMID:34868332, , (2021),
PMID: 34868332
Cosmeceutical activities of ethanol extract and its ethyl acetate fraction from coffee silverskIn. In Biol Trace Elem Res on 2019 Feb by Xuan SH, Lee KS, et al..PMID:30675376, , (2019),
PMID: 30675376
Ameliorative effects of nano-selenium agaInst NiSO4-Induced apoptosis In rat testes. In Toxicol Mech Methods on 2019 Jun 4 by Zhang X, Gan X, et al.. PMID: 31050317, , (2019),
PMID: 31050317
Synergistic effect of STAT3?targeted small InterferIng RNA and AZD0530 agaInst glioblastoma in vitro and In vivo. In Mol Med Rep on 2019 Oct by Liu , Wang L, et al..PMID:31485668, , (2019),
PMID: 31485668
A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
PMID: 31594861
Artemether Activation of AMPK/GSK3β(ser9)/Nrf2 SignalIng Confers Neuroprotection towards β-Amyloid-Induced Neurotoxicity In 3xTg Alzheimer's Mouse Model. In Oxid Med Cell Longev on 2019 Nov 21 by Li S, Zhao X, et al..PMID:31871541, , (2019),
PMID: 31871541
Melatonin ameliorates Aβ1 42 induced Alzheimer's cognitive deficits in mouse model.In J Pharm Pharmacol.On 2018 Jan by Gong YH, Hua N et al..PMID: 28994117 , , (2018),
PMID: 28994117
Sulforaphane-induced apoptosis in X uanwei lung adenocarcinoma cell line XWLC-05.In Thorac Cancer on 2017 Jan by Lan Zhou, Qian Yao,et al..PMID: 27878984, , (2017),
PMID: 27878984
D5 receptor agonist 027075 promotes cognitive function recovery and neurogenesis in a Aβ1-42-induced mouse model.In Neuropharmacology on 2016 Jun by Ling Shen , Ming Yan et al..PMID: 26773200, , (2016),
PMID: 26773200
miR-137 and miR-197 induce apoptosis and suppress tumorigenicity by targeting MCL-1 in multiple myeloma.In Clin Cancer Res on 2015 May 15 by Yijun Yang , Fei Li et al..PMID:25724519 , , (2015),
PMID: 25724519
Cryptotanshinone Inhibits Lung Tumorigenesis and Induces Apoptosis in Cancer Cells in Vitro and in Vivo.In Mol Med Rep on 2014 Jun by Liang Chen , Hui-Juan Wang et al..PMID:24682389, , (2014),
PMID: 24682389
Necroptosis inhibitor necrostatin-1 promotes cell protection and physiological function in traumatic spinal cord injury.In Neuroscience.On 2014 Apr 25 by Wang Y, Wang H et al..PMID:24561219, , (2014),
PMID: 24561219
Silencing HIWI suppresses the growth, invasion and migration of glioma cells.In Int J Oncol on 2014 Dec by Xiuyu Wang , Xiaoguang Tong et al..PMID:25269862, , (2014),
PMID: 25269862
Quercetin induces apoptosis via the mitochondrial pathway in KB and KBv200 cells.In J Agric Food Chem on 2013 Mar 6 by Zhang JY, Yi T,et al..PMID:23410218, , (2013),
PMID: 23410218
Lentivirus-mediated Sirt1 shRNA and resveratrol independently induce porcine preadipocyte apoptosis by canonical apoptotic pathway. In Mol Biol Rep on 2013 Jan by Wei-Jun Pang, Yan Xiong, et al..PMID: 23065251, , (2013),
PMID: 23065251
Please let us know if you have published research using #40639 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep