• Product NameHydroxyurea
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityHydroxyurea is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 127-07-1
• Calculated MW 76.06
• Formulation CH4N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:NC(=O)NO
  Pathways:DNA Damage/DNA Repair
  Receptor:ribonucleoside diphosphate reductase
  Boling pt:
  Melting pt:135-140C
  Solubility:Water: 15 mg/mL (197.23 mM); DMSO: 15 mg/mL (197.23 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Culligan K, et al. Plant Cell. 2004 May;16(5):1091-104.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting