• Product NameNS 11394
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors.
• Target NameGABA Receptor antagonist
• CAS No. 951650-22-9
• Calculated MW 353.42
• Formulation C23H19N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)(O)C1=CC2=C(C=C1)N(C=N2)C1=CC=CC(=C1)C1=CC=CC=C1C#N
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:GABAA
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Off-white Color Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Munro G, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):969-81.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting