• Product NameGSK-2636771
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityGSK2636771 is a potent, orally bioavailable, PI3Kβ-selective inhibitor, sensitive to PTEN null cell lines. Phase 1/2a.
• Target NamePI3K inhibitor
• CAS No. 1372540-25-4
• Calculated MW 433.42
• Formulation C22H22F3N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=NC2=C(C=C(C=C2C(O)=O)N2CCOCC2)N1CC1=C(C)C(=CC=C1)C(F)(F)F
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:PI3Kβ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 28 mg/mL (64.6 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Macauley D, et al. Drugs Fut, 2012, 37(6), 451.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting