• Product NameSW033291
• Brief DescriptionInhibitors
• Purification97.26%
• Biological ActivitySW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
• Target NameDehydrogenase inhibitor
• CAS No. 459147-39-8
• Calculated MW 412.59
• Formulation C21H20N2OS3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCCCS(=O)C1=C(N)C2=C(S1)N=C(C=C2C1=CC=CC=C1)C1=CC=CS1
  Pathways:Metabolism
  Receptor:15-PGDH; 15-PGDH
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhang Y, et al. Science. 2015 Jun 12;348(6240):aaa2340.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting