• Product NameMK5046
• Brief DescriptionInhibitors
• Purification99.91%
• Biological ActivityMK-5046 is a novel BRS-3 agonist, binds to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).
• Target NameBombesin Receptor agonist
• CAS No. 1022152-70-0
• Calculated MW 444.37
• Formulation C20H18F6N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1CC1(CC2=CN=C(N2)C[C@](C3=CC=C(C=C3)N4C=CC=N4)(C(F)(F)F)O)C(F)(F)F
  Pathways:GPCR/G Protein
  Receptor:BRS-3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Guan XM, et al. J Pharmacol Exp Ther. 2011 Feb;336(2):356-364.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting