• Product NameTriptolide (PG490)
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTriptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
• Target NameHSP inhibitor; Mdm2 inhibitor
• CAS No. 38748-32-2
• Calculated MW 360.4
• Formulation C20H24O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(CCC6=C([C@@H]5C[C@H]7[C@]4([C@@H]2O)O7)COC6=O)C
  Pathways:Cytoskeletal Signaling; Apoptosis; Metabolism
  Receptor:heat shock factor (HSF1)( in ALL cell lines); Mdm2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 72 mg/mL warmed (199.77 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Qiu D, et al. J Biol Chem, 1999, 274(19), 13443-13450.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting