• Product NameSalermide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySalermide is an inhibitor of Sirt1 and Sirt2; can cause strong cancer-specific apoptotic cell death.
• Target NameSirtuin inhibitor
• CAS No. 1105698-15-4
• Calculated MW 394.474
• Formulation C26H22N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(C1=CC=CC=C1)C(=O)NC2=CC=CC(=C2)N/C=C/3\C(=O)C=CC4=CC=CC=C43
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:SIRT1; SIRT2
  Boling pt:
  Melting pt:
  Solubility:DMSO:10 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lara E, et al. Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Oncogene. 2009 Feb 12;28(6):781-91.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting