• Product NameTirasemtiv
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTirasemtiv(CK 2017357) is a a small-molecule fast-skeletal-troponin activator, which is being developed as a potential treatment for diseases and conditions associated with aging, muscle weakness and wasting or neuromuscular dysfunction
• Target NameOthers
• CAS No. 1005491-05-3
• Calculated MW 230.271
• Formulation C12H14N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCC(CC)N1C2=NC(=CN=C2NC1=O)C#C
  Pathways:Others
  Receptor:Troponin
  Boling pt:
  Melting pt:
  Solubility:DMSO: 52 mg/Ml
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Russell AJ, et al. Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases. Nat Med. 2012 Feb 19;18(3):452-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting