• Product NameXL-652
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBMS-779788 is a LXR partial agonist with IC50 values of 68 nM for LXRα and 14 nM for LXRβ.
• Target NameLiver X Receptor agonist
• CAS No. 918348-67-1
• Calculated MW 509.06
• Formulation C28H29ClN2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:cardiovascular system
  SMILES:OC(C)(C)C1=CN(C2=CC=C(C3=CC=CC(S(=O)(C)=O)=C3)C=C2)C(C(C)(C4=CC=CC=C4Cl)C)=N1
  Pathways:Others
  Receptor:LXRα; LXRβ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 31 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kirchgessner TG,et al. Pharmacological characterization of a novel liver X receptor agonist with partial LXRα activity and a favorable window in nonhuman primates. J Pharmacol Exp Ther. 2015 Feb;352(2):305-14.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting