• Product NameGlucose-6-phosphate isomerase Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Glucose-6-phosphate isomerase polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Glucose-6-phosphate isomerase
• Target NameGlucose-6-phosphate isomerase
• Alternative Names    Autocrine motility factor, Phosphoglucose isomerase, Phosphohexose isomerase, Sperm antigen 36
• Accession No. Swiss-Prot#: P06744
• UniprotP06744
• Gene ID2821;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.

[1] "Cloning of a glucose phosphate isomerase/neuroleukin-like sperm antigen involved in sperm agglutination."Yakirevich E., Naot Y.Biol. Reprod. 62:1016-1023(2000) [2] "Complete sequencing and characterization of 21,243 full-length human cDNAs."Ota T., S

• Immunohistochemical analysis of paraffin-embeded human kidney using #42090 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting