• Product NameU1 small nuclear ribonucleoprotein A Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total U1 small nuclear ribonucleoprotein A polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human U1 small nuclear ribonucleoprotein A protein
• Target NameU1 small nuclear ribonucleoprotein A
• Alternative Names    SNRPA, U1 snRNP A, U1-A, U1A
• Accession No. Swiss-Prot#: P09012
• UniprotP09012
• Gene ID6626;
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:20 - 1:200

Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.

[1]"Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein."Nelissen R.L.H., Sillekens P.T.G., Beijer R.P., Geurts van Kessel A.H.M., van Venrooij W.J.Gene 102:189-196(1991)[2

• Immunohistochemical analysis of paraffin-embedded human kidney using #42190 at dilution of 1:100.
• Immunohistochemical analysis of paraffin-embedded human prostate using #42190 at dilution of 1:100.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting