• Product NameRecombinant Human UBXN1
• Brief DescriptionRecombinant Protein
• Immunogen DescriptionFull length fusion protein(1-312)
• Target NameUBX domain protein 1
• Alternative Names    2B28; SAKS1; UBXD10
• Accession No. Swissprot:Q04323
  Gene Accession:BC001372
• UniprotQ04323
• Gene ID51035;
• Storage -20~-80˚C, pH 7.6 PBS

Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

Note: For in vitro research use only, not for diagnostic or therapeutic use. This product is not a medical device.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting