• Product NameIntegrin Alpha V + Beta 5 Antibody FITC Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFlow-Cyt IF
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V
• ConjugatesFITC
• Excitation Emission494nm 518nm
• Target NameIntegrin Alpha V + Beta 5
• Alternative Names    CD51; MSK8; VNRA; VTNR; Integrin alpha-V; Vitronectin receptor subunit alpha; ITGAV
• Accession No. Swiss-Prot#P06756
  NCBI Gene ID3685
• UniprotP06756
• Gene ID3685;
• Cell Localization Extracellular
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• Flow-Cyt=1:50-200 IF=1:50-200

The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting