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NFκB-p105(Phospho-Ser893) Antibody#11018

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Product Detail

Product NameNFκB-p105(Phospho-Ser893) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsIHC IF

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total NFκB-p105 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.891~895 (A-S-S-P-V) derived from Human NFκB-p105.

Target NameNFκB-p105

ConjugateUnconjugated

Other NamesKBF1; NF-kB1; NFkappaB

Accession NoSwiss-Prot#: P19838; NCBI Gene#: 4790

Uniprot P19838

Gene ID 4790;

Sdspage MW120kd

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C

Application Details
 
Immunohistochemistry:1:50~1:100
Immunofluorescence:1:100~1:200
 
Immunofluorescence staining of methanol-fixed HeLa cells using NF-κB p105 (phospho-Ser893) antibody (#11018 Red).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NF-κB p105 (phospho-Ser893) antibody (#11018).

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

If you have published an article using product 11018, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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