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synapsin(Phospho-Ser9) Antibody#11267

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Product Detail

Product Namesynapsin(Phospho-Ser9) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

ApplicationsWB IF

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of synapsin only when phosphorylated at serine 9.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around phosphorylation site of serine 9 (R-L-S(p)-D-S) derived from Human SYN1/synapsin.

Target Namesynapsin

ConjugateUnconjugated

Other NamesSyn-1, synapsin I

Accession NoSwiss-Prot: P17600
NCBI Protein: NP_008881.2

Uniprot P17600

Gene ID 6853;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details
Predicted MW: 77kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200
Western blot analysis of extracts from Mouse Brain tissue using synapsin(Phospho-Ser9) Antibody #11267.
Immunofluorescence staining of methanol-fixed Hela cells using synapsin(Phospho-Ser9) Antibody #11267.
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level

Diviya Sinha, et,al. (2005) Am J Physiol Renal Physiol ; 288: F703 - F713.
Franco Onofri, et,al. (2000) J. Biol. Chem ; 275: 29857.
Dario Bonanomi, et,al. (2005) J. Neurosci; 25: 7299 - 7308.
Hiroshi Tokumitsu, et,al. (2005) J. Biol. Chem ; 280: 35108 - 35118.

If you have published an article using product 11267, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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