Product NameSHP-2(Phospho-Tyr580) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

ApplicationsWB IHC

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of SHP-2 only when phosphorylated at tyrosine 580.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around phosphorylation site of tyrosine 580 (R-V-Y(p)-E-N) derived from Human SHP-2.

Target NameSHP-2

ConjugateUnconjugated

Other NamesPTN11; PTP-1D; PTP-2C; PTP2C; PTPN11

Accession NoSwiss-Prot: Q06124
NCBI Protein: NP_002825.3

Uniprot Q06124

Gene ID 5781;

Calculated MWPredicted MW: 72kd

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

WB 1:500-1:2000;
IHC 1:100-1:300