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Calcium Sensing Receptor (Phospho-Thr888) Antibody#12041

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Product Detail

Product NameCalcium Sensing Receptor (Phospho-Thr888) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

ApplicationsWB

Species ReactivityHu

SpecificityThe antibody detects endogenous level of Calcium Sensing Receptor only when phosphorylated at Threonine 888.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around phosphorylation site of Threonine 888 (R-A-T(p)-L-R) derived from Human Calcium Sensing Receptor.

Target NameCalcium Sensing Receptor

ConjugateUnconjugated

Other NamesCAR, FHH, FIH, HHC, EIG8

Accession NoSwiss-Prot#: P41180;
NCBI Gene#: 846;
NCBI Protein#: NP_000379.2

Uniprot P41180

Gene ID 846;

Sdspage MW140kd

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20˚C/1 year

Application Details
Predicted MW: 140kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from LOVO cells using Calcium Sensing Receptor (Phospho-Thr888) Antibody #12041.The lane on the left is treated with the antigen-specific peptide.
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

If you have published an article using product 12041, please notify us so that we can cite your literature.

et al,Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor.In J Pharmacol Sci on 2015 Apr by Ming Zhao , Xi He et al..PMID:25922231 , (2015),
PMID: 25922231

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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