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IL-8R beta/CDw128 beta (Phospho-Ser347) Antibody#12051

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Product Detail

Product NameIL-8R beta/CDw128 beta (Phospho-Ser347) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

ApplicationsWB

Species ReactivityHu Ms

SpecificityThe antibody detects endogenous level of IL-8R beta/CDw128 beta only when phosphorylated at Serine 347.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around phosphorylation site of Serine 347 (R-P-S(p)-F-V) derived from Human IL-8R beta/CDw128 beta

Target NameIL-8R beta/CDw128 beta

Other NamesCD182, IL8R2, IL8RA, IL8RB, CMKAR2

Accession NoSwiss-Prot#: P25025;
NCBI Gene#: 3579;
NCBI Protein#: NP_001161770.1

Uniprot P25025

Gene ID 3579;

Sdspage MW48kd

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20˚C/1 year

Application Details
Predicted MW: 48kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from 3T3 cells treated with UV using IL-8R beta/CDw128 beta (Phospho-Ser347) Antibody #12051.The lane on the left is treated with the antigen-specific peptide.
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

If you have published an article using product 12051, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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