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PERK (Phospho-Thr982) Polyclonal Antibody#12379

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Product NamePERK (Phospho-Thr982) Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ApplicationsWB IHC

Species ReactivityHu Ms Rt

SpecificityPhospho-PERK (T982) Polyclonal Antibody detects endogenous levels of PERK protein only when phosphorylated at T982.

Immunogen DescSynthesized peptide derived from human PERK around the phosphorylation site of T982.

Target NamePERK

ConjugateUnconjugated

Other NamesEIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK

Accession NoSwiss-Prot: Q9NZJ5
NCBI Gene ID: 9451

Uniprot Q9NZJ5

Gene ID 9451;

Sdspage MW125kd

Concentration1mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20˚C/1 year

Target Specieshuman

Application Details
Western Blot: 1:500-2000
Immunohistochemistry: 1/100 - 1/300
Western Blot analysis of 453 AD293 cells using Phospho-PERK (T982) Polyclonal Antibody

If you have published an article using product 12379, please notify us so that we can cite your literature.

et al,High glucose and bupivacaIne?Induced cytotoxicity is mediated by enhanced apoptosis and impaired autophagy via the PERK?ATF4?CHOP and IRE1?TRAF2 signalIng pathways. In Mol Med Rep on 2019 Sep by Liu Y, Sun L, et al..PMID:31524237 , (2019),
PMID: 31524237
et al,Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet?induced obese mice via endoplasmic reticulum stress and p?STAT3/STAT3 signaling.In Mol Med Rep on 2020 Mar; by Yao Y et al..PMID:32016448 , (2020),
PMID: 32016448
et al,Qing Hua Chang Yin ameliorates chronic colitis in mice by inhibiting PERK–ATF4–CHOP pathway of ER stress and the NF-κB signalling pathway. In Pharm Biolon 2024 Dec by Liya Liu, Youqin Chen,et al..PMID:39034914 , (2024),
PMID: 39034914
et al,Lentinan inhibited colon cancer growth by inducing endoplasmic reticulum stress-mediated autophagic cell death and apoptosis , (2021),
PMID: 34119128
et al,Artemisinin alleviates astrocyte overactivation and neuroinflammation by modulating the IRE1/NF-κB signaling pathway in in vitro and in vivo Alzheimer's disease models. , (2025),
PMID: 39826816
et al,CUMS induces depressive-like behaviors and cognition impairment by activating the ERS-NLRP3 signaling pathway in mice. , (2025),
PMID: 39378914

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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