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DRP1 (Phospho-Ser616) Antibody#12749

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Product Detail

Product NameDRP1 (Phospho-Ser616) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityDRP1 (Phospho-Ser616) Antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616

Immunogen TypePeptide

Immunogen DescA synthesized peptide derived from human DRP1 (Phospho-Ser616)

Target NameDRP1

ConjugateUnconjugated

Other NamesDNM1L, DYMPLE, Dynamin 1-like, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, DLP1, Dnm1p/Vps1p-like protein, DVLP, Dynamin-related protein 1, DYNIV-11, DRP1, Dynamin-1-like protein, VPS1, EMPF, HDYNIV

Accession NoSwiss-Prot#: O00429
NCBI Gene ID: 10059

Uniprot O00429

Gene ID 10059;

Calculated MW79kd

Concentration1.0mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20˚C

Target Specieshuman

Application Details

Western blotting: 1:1000

Western Blot analysis of hela cells, hela cell treated or untreated by Nocodazole at 100 ng/ml 17h. Primary Antibody was diluted at 1:1000. Secondary antibody(catalog#:RS23920 was diluted at 1:10000

If you have published an article using product 12749, please notify us so that we can cite your literature.

et al,Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.In Biol Sex Differ. On 2018 Jan 19 by Pesaresi M1, Giatti S et al..PMID:29351809 , (2018),
PMID: 29351809
et al,PyridostigmIne regulates glucose metabolism and mitochondrial homeostasis to reduce myocardial vulnerability to Injury In diabetic mice. In Am J Physiol EndocrInol Metab on 2019 Aug 1 by Yang Y, Zhao M et al..PMID:31211620 , (2019),
PMID: 31211620
et al,Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis.In Theranostics on 2020 Jan 1; by Dong L, Li P, et al..PMID: 31938063 , (2020),
PMID: 31938063
et al,Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.In Int J Biol Sci on 2020 Feb 21; by Deng X, Liu J, et al..PMID:32210728 , (2020),
PMID: 32210728
et al,ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension. In Cell Prolif on 2021 Jun by Wei Feng, Jian Wang,et al..PMID: 33948998 , (2021),
PMID: 33948998
et al,Ketone Body Improves Neurological Outcomes after Cardiac Arrest by Inhibiting Mitochondrial Fission in Rats. In Oxid Med Cell Longev on 2022 Jul 7 by Yunke Tan, Jie Zhang,et al..PMID:35847595 , (2022),
PMID: 35847595
et al,Levosimendan protects from sepsis-inducing cardiac dysfunction by suppressing inflammation, oxidative stress and regulating cardiac mitophagy via the PINK-1-Parkin pathway in mice. In Ann Transl Med on 2022 Feb by Jian Shi, Yuhong Chen, et al..PMID:35280364 , (2022),
PMID: 35280364
More
et al,Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsisIn EMBO RepOn2023 Aug 3byChao Fang , Pan Ren et al..PMID:37358015 , (2023),
PMID: 37358015
et al,AMPD3 promotes doxorubicin-induced cardiomyopathy through HSP90α-mediated ferroptosis. In Sci Total Environ on 2024 Sep 15 by Liting Cheng, Mingxiang Zhu,et al..PMID:39474068 , (2024),
PMID: 39474068
et al,Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway , (2023),
PMID:
et al,Mito-Apocynin Protects Against Kainic Acid-Induced Excitotoxicity by Ameliorating Mitochondrial Impairment. , (2025),
PMID: 40095344

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;