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Location： Home > Phospho Antibodies > GluR1(Phospho-S845) Rabbit mAb

GluR1(Phospho-S845) Rabbit mAb#13418

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Product Detail

Product NameGluR1(Phospho-S845) Rabbit mAb

Clone No.JJ2009

Host SpeciesRabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB

Species ReactivityHu, Ms, Rt

Immunogen DescSynthetic phospho-peptide corresponding to residues surrounding Ser845 of human GluR1.

ConjugateUnconjugated

Other NamesGLUR 1 antibody
GLUR A antibody
AMPA 1 antibody
AMPA selective glutamate receptor 1 antibody
AMPA-selective glutamate receptor 1 antibody
GluA1 antibody
GLUH1 antibody
GluR K1 antibody
GluR-1 antibody
GluR-A antibody
GluR-K1 antibody
GLUR1 antibody
GLURA antibody
GluRK1 antibody
Glutamate receptor 1 antibody
Glutamate receptor ionotropic AMPA 1 antibody
Glutamate receptor ionotropic antibody
Glutamate receptor, ionotropic, AMPA 1 antibody
Gria1 antibody
GRIA1_HUMAN antibody
HBGR1 antibody
MGC133252 antibody
OTTHUMP00000160643 antibody
OTTHUMP00000165781 antibody
OTTHUMP00000224241 antibody
OTTHUMP00000224242 antibody
OTTHUMP00000224243 antibody

Accession NoSwiss-Prot#:P42261

Uniprot P42261

Gene ID 2890;

Calculated MWPredicted band size: 102 kDa

Sdspage MWObserved band size: 102 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2000
All lanes : GluR1(Phospho-S845) Rabbit mAb at 1/500 dilution

Lane 1 : Mouse brain tissue lysates
Lane 2 : Mouse brain tissue lysates treated with λpp for 1 hour

Lysates/proteins at 20 µg per lane.

Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) at 1/20000 dilution

Predicted band size: 102 kDa
Observed band size: 102 kDa

Exposure time: 15 seconds
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

If you have published an article using product 13418, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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