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MLKL (phospho-S345) Rabbit mAb#13433

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Product NameMLKL (phospho-S345) Rabbit mAb

Clone No.JM92-37

Host SpeciesRabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsIHC

Species ReactivityMs

Immunogen DescSynthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL.

ConjugateUnconjugated

Other Names9130019I15Rik antibody
FLJ34389 antibody
hMLKL antibody
Mixed lineage kinase domain like antibody
Mixed lineage kinase domain like protein antibody
Mixed lineage kinase domain like pseudokinase antibody
Mixed lineage kinase domain-like protein antibody
Mlkl antibody
MLKL_HUMAN antibody

Accession NoSwiss-Prot#:Q9D2Y4

Uniprot Q9D2Y4

Gene ID 74568;

Calculated MW54 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

IHC: 1:50-1:100


Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-MLKL (phospho S345) antibody. Counter stained with hematoxylin.
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

If you have published an article using product 13433, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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