Product Detail
Product NameTyk2 (phospho-Tyr1054/1055) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman
SpecificityThis antibody detects endogenous levels of Human Tyk2 (phospho-Tyr1054 or 1055)
Immunogen DescSynthesized phosho peptide around human Tyk2 (Tyr1054 and 1055)
ConjugateUnconjugated
Other NamesNon-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
Accession NoSwiss Prot:P29597
GeneID:7297
Uniprot
P29597
Gene ID
7297
Sdspage MW134
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
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Yes
