Product Detail
Product NameTrk A (Phospho-Y496) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
ApplicationsWB, ELISA
Species ReactivityHuman, Mouse, Rat
SpecificityThis antibody detects endogenous pospho levels of human Trk A (Phospho-Y496)
Immunogen DescSynthesized pospho peptide derived from human Trk A (Phospho-Y496)
ConjugateUnconjugated
Other NamesHigh affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Accession NoSwiss Prot:P04629
GeneID:4914
Uniprot
P04629
Gene ID
4914
Sdspage MW180
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:500-2000,
ELISA(peptide)1:5000-20000
neurotrophic receptor tyrosine kinase 1(NTRK1) Homo sapiens This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008],
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