Product Detail
Product NameTF (phospho Ser290) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB,IHC-p,IF(paraffin section),ELISA
Species ReactivityHuman
SpecificityPhospho-TF (S290) Polyclonal Antibody detects endogenous levels of TF protein only when phosphorylated at S290.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Coagulation Factor III around the phosphorylation site of Ser290. AA range:246-295
ConjugateUnconjugated
Other NamesF3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142
Accession NoSwiss Prot:P13726
GeneID:2152
Uniprot
P13726
Gene ID
2152
Sdspage MW40
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Western Blot: 1/500 - 1/2000.
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/20000. Not yet tested in other applications.
coagulation factor III, tissue factor(F3) Homo sapiens This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
If you have published an article using product 13483, please notify us so that we can cite your literature.
Yes
