Product Detail
Product NameTBK1/NAK (phospho-Ser172) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse
SpecificityThis antibody detects endogenous levels of Human Mouse TBK1/NAK (phospho-Ser172)
Immunogen DescSynthesized phosho peptide around human TBK1 and NAK (Ser172)
ConjugateUnconjugated
Other NamesSerine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Accession NoSwiss Prot:Q9UHD2
GeneID:29110
Uniprot
Q9UHD2
Gene ID
29110
Sdspage MW80
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
TANK binding kinase 1(TBK1) Homo sapiens The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],
If you have published an article using product 13488, please notify us so that we can cite your literature.
et al,Activation of cGAS-STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy. In J Clin Lab Anal on 2022 Oct by Meichen Zhou, Xiaoxiao Cheng, et al..PMID:36030554
, (2022),
PMID:
36030554
Yes
