Product Detail
Product NameStat2 (phospho Tyr631) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC, IF, ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-Stat2 (Y631) Polyclonal Antibody detects endogenous levels of Stat2 protein only when phosphorylated at Y631.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr631. AA range:597-646
ConjugateUnconjugated
Other NamesSTAT2; Signal transducer and activator of transcription 2; p113
Accession NoSwiss Prot:P52630
GeneID:6773
Uniprot
P52630
Gene ID
6773
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
IHC 1:100-1:300;
ELISA 1:40000; IF 1:50-200
signal transducer and activator of transcription 2(STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
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