Product Detail
Product NameRibosomal Protein S6 (phospho Ser235) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB,IF/ICC,ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-Ribosomal Protein S6 (S235) Polyclonal Antibody detects endogenous levels of Ribosomal Protein S6 protein only when phosphorylated at S235.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein around the phosphorylation site of Ser235. AA range:200-249
ConjugateUnconjugated
Other NamesRPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33
Accession NoSwiss Prot:P62753
GeneID:6194
Uniprot
P62753
Gene ID
6194
Sdspage MW32
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Western Blot: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: 1/20000. Not yet tested in other applications.
ribosomal protein S6(RPS6) Homo sapiens Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed
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