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Location： Home > Phospho Antibodies > Rb (phospho Ser608) Polyclonal Antibody

Rb (phospho Ser608) Polyclonal Antibody#13574

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Product Detail

Product NameRb (phospho Ser608) Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ApplicationsWB,IHC-p,IF(paraffin section),ELISA

Species ReactivityHuman,Mouse,Rat

SpecificityPhospho-Rb (S608) Polyclonal Antibody detects endogenous levels of Rb protein only when phosphorylated at S608.

Immunogen DescThe antiserum was produced against synthesized peptide derived from human Retinoblastoma around the phosphorylation site of Ser608. AA range:581-630

ConjugateUnconjugated

Other NamesRB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Accession NoSwiss Prot:P06400
GeneID:5925

Uniprot P06400

Gene ID 5925

Sdspage MW110

Concentration1 mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage-20˚C/1

Application Details
Western Blot: 1/500 - 1/2000.
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/40000. Not yet tested in other applications.
RB transcriptional corepressor 1(RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

If you have published an article using product 13574, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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