Product Detail
Product NamePKCα/β II (phospho-Thr638/641) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse
SpecificityThis antibody detects endogenous levels of Human Mouse PKCα/β II (phospho-Thr638 or 641)
Immunogen DescSynthesized phosho peptide around human PKCα (Thr638 and 641)
ConjugateUnconjugated
Other NamesProtein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Accession NoSwiss Prot:P17252
GeneID:5578
Uniprot
P17252
Gene ID
5578
Sdspage MW76
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
protein kinase C alpha(PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2
If you have published an article using product 13613, please notify us so that we can cite your literature.
Yes
