Product Detail
Product NameMucin 1 (phospho Ser1227) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC;IF;ELISA
Species ReactivityHuman
SpecificityPhospho-Mucin 1 (S1227) Polyclonal Antibody detects endogenous levels of Mucin 1 protein only when phosphorylated at S1227.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human MUC1 around the phosphorylation site of Ser1227. AA range:1196-1245
ConjugateUnconjugated
Other NamesMUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated ep
Accession NoSwiss Prot:P15941
GeneID:4582
Uniprot
P15941
Gene ID
4582
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
IHC 1:100-1:300;
ELISA 1:5000; IF 1:50-200
mucin 1, cell surface associated(MUC1) Homo sapiens This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp
If you have published an article using product 13697, please notify us so that we can cite your literature.
Yes
