Product Detail
Product NameInsulin Receptor β (phospho-Tyr1345) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman
SpecificityThis antibody detects endogenous levels of Human Insulin Receptor β (phospho-Tyr1345)
Immunogen DescSynthesized phosho peptide around human Insulin Receptor β (Tyr1345)
ConjugateUnconjugated
Other NamesInsulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Accession NoSwiss Prot:P06213
GeneID:3643
Uniprot
P06213
Gene ID
3643
Sdspage MW95
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
insulin receptor(INSR) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
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Yes
