Product Detail
Product NameIGF-IR (phospho Tyr1346) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC;IF;ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-IGF-IR (Y1346) Polyclonal Antibody detects endogenous levels of IGF-IR protein only when phosphorylated at Y1346.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1346. AA range:1311-1360
ConjugateUnconjugated
Other NamesIGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Accession NoSwiss Prot:P08069
GeneID:3480
Uniprot
P08069
Gene ID
3480
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
IHC 1:100-1:300;
ELISA 1:40000; IF 1:50-200
insulin like growth factor 1 receptor(IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
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Yes
