Product Detail
Product NameGRB10 (phospho-Ser476) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse
SpecificityThis antibody detects endogenous levels of Human Mouse GRB10 (phospho-Ser476)
Immunogen DescSynthesized phosho peptide around human GRB10 (Ser476)
ConjugateUnconjugated
Other NamesGrowth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
Accession NoSwiss Prot:Q13322
GeneID:2887
Uniprot
Q13322
Gene ID
2887
Sdspage MW67
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
growth factor receptor bound protein 10(GRB10) Homo sapiens The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010],
If you have published an article using product 13833, please notify us so that we can cite your literature.
Yes
