Product Detail
Product NameeIF4G (phospho-Ser1108) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
SpecificityThis antibody detects endogenous levels of Human Mouse Rat eIF4G (phospho-Ser1108)
Immunogen DescSynthesized phosho peptide around human eIF4G (Ser1108)
ConjugateUnconjugated
Other NamesEukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Accession NoSwiss Prot:Q04637
GeneID:1981
Uniprot
Q04637
Gene ID
1981
Sdspage MW180
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
eukaryotic translation initiation factor 4 gamma 1(EIF4G1) Homo sapiens The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010],
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