Product Detail
Product NameDR6 (phospho-Ser562) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
SpecificityThis antibody detects endogenous levels of Human Mouse Rat DR6 (phospho-Ser562)
Immunogen DescSynthesized phosho peptide around human DR6 (Ser562)
ConjugateUnconjugated
Other NamesTumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
Accession NoSwiss Prot:O75509
GeneID:27242
Uniprot
O75509
Gene ID
27242
Sdspage MW72
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
TNF receptor superfamily member 21(TNFRSF21) Homo sapiens This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],
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