Product Detail
Product NameDNAJC2/MPP11 (phospho-Ser47) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
SpecificityThis antibody detects endogenous levels of Human Mouse Rat DNAJC2/MPP11 (phospho-Ser47)
Immunogen DescSynthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)
ConjugateUnconjugated
Other NamesDnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)
Accession NoSwiss Prot:Q99543
GeneID:27000
Uniprot
Q99543
Gene ID
27000
Sdspage MW68
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
DnaJ heat shock protein family (Hsp40) member C2(DNAJC2) Homo sapiens This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],
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