Product Detail
Product NameDab1 (phospho-Tyr220) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman
SpecificityThis antibody detects endogenous levels of Human Dab1 (phospho-Tyr220)
Immunogen DescSynthesized phosho peptide around human Dab1 (Tyr220)
ConjugateUnconjugated
Other NamesDisabled homolog 1
Accession NoSwiss Prot:O75553
GeneID:1600
Uniprot
O75553
Gene ID
1600
Sdspage MW60
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
DAB1, reelin adaptor protein(DAB1) Homo sapiens The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
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