Product Detail
Product NameDab1 (phospho Tyr232) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB,IF/ICC,ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Dab1 around the phosphorylation site of Tyr232. AA range:199-248
ConjugateUnconjugated
Other NamesDAB1; Disabled homolog 1
Accession NoSwiss Prot:O75553
GeneID:8674
Uniprot
O75553
Gene ID
8674
Sdspage MW60
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Western Blot: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: 1/20000. Not yet tested in other applications.
DAB1, reelin adaptor protein(DAB1) Homo sapiens The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
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