Product Detail
Product Namec-Rel (phospho Ser503) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB;IHC;IF;ELISA
Species ReactivityHuman
SpecificityPhospho-c-Rel (S503) Polyclonal Antibody detects endogenous levels of c-Rel protein only when phosphorylated at S503.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Rel around the phosphorylation site of Ser503. AA range:470-519
ConjugateUnconjugated
Other NamesREL; Proto-oncogene c-Rel
Accession NoSwiss Prot:Q04864
GeneID:5966
Uniprot
Q04864
Gene ID
5966
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:500-1:2000;
IHC 1:100-1:300;
ELISA 1:5000; IF 1:50-200
REL proto-oncogene, NF-kB subunit(REL) Homo sapiens This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014],
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