Product Detail
Product Namec-Myc (phospho Ser373) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC-p,IF(paraffin section),IP,ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-c-Myc (S373) Polyclonal Antibody detects endogenous levels of c-Myc protein only when phosphorylated at S373.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Myc around the phosphorylation site of Ser373. AA range:340-389
ConjugateUnconjugated
Other NamesMYC; BHLHE39; Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
Accession NoSwiss Prot:P01106
GeneID:4609
Uniprot
P01106
Gene ID
4609
Sdspage MW50,
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Immunohistochemistry: 1/100 - 1/300.
Immunoprecipitation: 2-5 ug/mg lysate.
ELISA: 1/20000. Not yet tested in other applications.
v-myc avian myelocytomatosis viral oncogene homolog(MYC) Homo sapiens The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008],
If you have published an article using product 13961, please notify us so that we can cite your literature.
Yes
