Product Detail
Product Namec-Fos (phospho Ser374) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC-p,IF(paraffin section),WB,ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-c-Fos (S374) Polyclonal Antibody detects endogenous levels of c-Fos protein only when phosphorylated at S374.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Fos around the phosphorylation site of Ser374. AA range:331-380
ConjugateUnconjugated
Other NamesFOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7
Accession NoSwiss Prot:P01100
GeneID:2353
Uniprot
P01100
Gene ID
2353
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:500-2000
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/10000. Not yet tested in other applications.
Fos proto-oncogene, AP-1 transcription factor subunit(FOS) Homo sapiens The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008],
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