Product Detail
Product NameCD4 (phospho Ser433) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC-p,IF/ICC,ELISA
Species ReactivityHuman,Mouse
SpecificityPhospho-CD4 (S433) Polyclonal Antibody detects endogenous levels of CD4 protein only when phosphorylated at S433.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human CD4 around the phosphorylation site of Ser433. AA range:401-450
ConjugateUnconjugated
Other NamesCD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD antigen CD4
Accession NoSwiss Prot:P01730
GeneID:920
Uniprot
P01730
Gene ID
920
Calculated MW51kd
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Immunohistochemistry: 1/100 - 1/300.
Immunofluorescence: 1/200 - 1/1000.
ELISA: 1/40000. Not yet tested in other applications.
CD4 molecule(CD4) Homo sapiens This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010],
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