Product Detail
Product NameCatenin-β (phospho Thr41/S45) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB,ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-Catenin-β (T41/S45) Polyclonal Antibody detects endogenous levels of Catenin-β protein only when phosphorylated at T41/S45.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Catenin-beta around the phosphorylation site of Thr41/Ser45. AA range:11-60
ConjugateUnconjugated
Other NamesCTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin
Accession NoSwiss Prot:P35222
GeneID:1499
Uniprot
P35222
Gene ID
1499
Sdspage MW85
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Western Blot: 1/500 - 1/2000.
ELISA: 1/20000. Not yet tested in other applications.
catenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
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