Product Detail
Product NameCatalase (phospho Tyr386) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB,IHC-p,IF(paraffin section),ELISA
Species ReactivityHuman,Mouse,Rat
SpecificityPhospho-Catalase (Y386) Polyclonal Antibody detects endogenous levels of Catalase protein only when phosphorylated at Y386.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Catalase around the phosphorylation site of Tyr385. AA range:361-410
ConjugateUnconjugated
Other NamesCAT; Catalase
Accession NoSwiss Prot:P04040
GeneID:847
Uniprot
P04040
Gene ID
847
Sdspage MW59
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Western Blot: 1/500 - 1/2000.
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/20000. Not yet tested in other applications.
catalase(CAT) Homo sapiens This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],
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Yes
