Product Detail
Product NameCaspase-2 (phospho Ser157) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC-p,IF(paraffin section),ELISA
Species ReactivityHuman
SpecificityPhospho-Caspase-2 (S157) Polyclonal Antibody detects endogenous levels of Caspase-2 protein only when phosphorylated at S157.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human Caspase 2 around the phosphorylation site of Ser157. AA range:123-172
ConjugateUnconjugated
Other NamesCASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
Accession NoSwiss Prot:P42575
GeneID:835
Uniprot
P42575
Gene ID
835
Calculated MW50kd
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/10000. Not yet tested in other applications.
caspase 2(CASP2) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],
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Yes
