Product Detail
Product NameCARD11 (phospho-Ser652) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
SpecificityThis antibody detects endogenous levels of Human Mouse Rat CARD11 (phospho-Ser652)
Immunogen DescSynthesized phosho peptide around human CARD11 (Ser652)
ConjugateUnconjugated
Other NamesCaspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)
Accession NoSwiss Prot:Q9BXL7
GeneID:84433
Uniprot
Q9BXL7
Gene ID
84433
Sdspage MW130
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
caspase recruitment domain family member 11(CARD11) Homo sapiens The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],
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Yes
