Product Detail
Product NameC3G (phospho Tyr504) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB,IHC-p,IF(paraffin section),ELISA
Species ReactivityHuman
SpecificityPhospho-C3G (Y504) Polyclonal Antibody detects endogenous levels of C3G protein only when phosphorylated at Y504.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519
ConjugateUnconjugated
Other NamesRAPGEF1; GRF2; Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G
Accession NoSwiss Prot:Q13905
GeneID:2889
Uniprot
Q13905
Gene ID
2889
Sdspage MW120
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
Western Blot: 1/500 - 1/2000.
ELISA: 1/10000. Not yet tested in other applications.
Rap guanine nucleotide exchange factor 1(RAPGEF1) Homo sapiens This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
If you have published an article using product 14033, please notify us so that we can cite your literature.
Yes
