Product Detail
Product NameAPC (phospho Ser2054) Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB;IHC;IF;ELISA
Species ReactivityHuman
SpecificityPhospho-APC (S2054) Polyclonal Antibody detects endogenous levels of APC protein only when phosphorylated at S2054.
Immunogen DescThe antiserum was produced against synthesized peptide derived from human APC around the phosphorylation site of Ser2054. AA range:2020-2069
ConjugateUnconjugated
Other NamesAPC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5
Accession NoSwiss Prot:P25054
GeneID:324
Uniprot
P25054
Gene ID
324
Sdspage MW311
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:500-1:2000;
IHC 1:100-1:300;
ELISA 1:40000; IF 1:50-200
APC, WNT signaling pathway regulator(APC) Homo sapiens This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008],
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The lead time is 1 month
